Our lab studies genetic and acquired cardiomyopathies in an effort to identify novel methods to prevent and treat hypertrophic cardiomyopathy and heart failure. We utilize a variety of experimental systems which include mouse, zebrafish, iPSC-cardiomyocytes and human tissue samples.
The primary goals of the lab are:
– Identify novel pathways involved in the pathogenesis of human cardiomyopathies.
– Develop methods to study these pathways using both in vitro and in vivo experimental model systems.
– Identify modifiers of these disease pathways which can serve as the foundation for novel therapeutic strategies.